Biden and Drug Makers Look to Speed Coronavirus Vaccine Deliveries

WASHINGTON – During his second week in office as President Biden, events flooded to vaccinate Production and distribution may mean that there was also a large boost a few days earlier than the coronovirus vaccine supply.

Modern, one of the two authorized federation developers Coronavirus vaccine, Is asking U.S. regulators to approve what it says could be a fairly straightforward proposal to speed up the vaccination of Americans against coronovirus: fill in the blanks in its vials because it has a 50 percent higher dose it occurs.

The modern one currently accounts for about half of the country’s vaccine stock. If the change is approved – which can happen in weeks – it could eventually add more than a million doses to supply the vaccine.

At the same time, the White House announced on Tuesday that it was listing more retail pharmacies as a channel to distribute vaccines. White House Coronavirus Response Coordinator Jeffrey D. Ziers said the federal government would send one million doses to about 6,500 retail pharmacies on 11 February. A federal program is expected to eventually deliver vaccines directly to 40,000 pharmacies.

White House announcements were made to clearly show that Mr. Biden was making rapid progress amid huge disappointment in the country over vaccine supplies and with a chaotic, cobbled-in system to administer available shots. Were. But events also indicated that the government was slowly expanding in such a way that people could get their immunity and the number of shots available.

The possibility of a greater supply is at least a silver lining that many Americans may not have to wait until midsummer or be vaccinated later, while new variants spread the virus more quickly and the nation dies She goes, Now about 445,000 people, Rises.

For weeks, many health experts inside and outside the federal government have despaired of the United States’ ability to produce more than 220 million doses that Pfizer and Modern say they want to deliver by the end of next month Are on track for The spring is important as health experts warn that the nation may be vulnerable to more contagious forms of the virus by then.

Because both Pfizer’s Modern and Modern vaccines require two doses, the companies have promised that only 110 million of the country’s 260 million adults will be covered. The third vaccine developer, Johnson & Johnson, is expected to soon approve the vaccine for its use, but will only be able to deliver seven million doses before April.

Modern to Fuller’s vials can brighten the outlook. As the company accelerated its drug manufacturing in recent weeks, officials said, it felt that the process of filling, capping and labeling millions of vials was a route to increase output. Late Monday evening Ray Jordan, who was a regulator for Jordan, a spokesman for the company, was raising regulators to increase the number of doses the vaccine could deliver more quickly.

Dr., who was the Assistant Health Secretary for preparedness and response under President Barack Obama. “It matters a lot,” said Nicole Lurie. If Modern could use the same size as the vial and the same production lines already running, he said, “It’s a relatively easy and straightforward fix.”

Prashant Yadav, who studies health care supply chains at the Center for Global Development in Washington, said that modernity should be able to make factory adjustments to produce fuller vials.

If too many doses are put in a vial, it can break. Modern authorities carried out a series of tests and the upper limit was set. 15. Unlike Pfizer, which is manufactured with a vial limited to about six doses, Moderna was large enough to hold the industry standard of 10 doses, according to people familiar with the operations of a few more companies.

As the Biden administration has somehow explored to increase production, addressing bottlenecks in the “fill and finish” phase of manufacturing has increasingly become a focal point. That nut-and-bolt stage itself receives less attention than the vaccine-making process itself, but has been recognized for years as a constraint on production.

Company officials have discussed paired dosage options with the Food and Drug Administration, but have not yet presented data to justify this, he said. Federal regulators may be receptive to the idea, but may approve more modest growth than modernity, partly out of concern that many additional puncture vaccines may be contaminated by rubber needles covering the vial May increase the risk.

When asked about Modern’s proposal, a White House spokesman only stated that “all options are on the table.”

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Answers to your vaccine questions

Currently more than 150 million people – about half the population – are eligible for vaccination. but Each state makes the final decision about who goes first. The country’s 21 million health care workers and three million residents of long-term care facilities were previously eligible. In mid-January, federal officials urged all states To open eligibility All adults 65 and older with medical conditions at high risk of becoming seriously ill or dying of Kovid-19. Adults in the general population are behind the line. If federal and state health officials can overcome bottlenecks in vaccine delivery, all 16 and older will become eligible by this spring or early summer. The vaccine has not been approved in children, although studies are ongoing. It may be months before the vaccine becomes available to anyone under 16 months of age. Go to your state health website For up-to-date information about vaccination policies in your area

You should not give anything out of pocket to get vaccinated, Although you will be asked for insurance information. Even if you do not have insurance, you should be given the vaccine at no charge. Congress passed legislation this spring to prohibit insurers from sharing any costs, such as co-pays or deductibles. It provides additional protection from billing patients to pharmacies, doctors and hospitals, including those. Still, health experts worry that patients may be weak Leave the bills surprising them. This can happen to people who are charged with a doctor visit with a vaccine, or Americans who have certain types of health coverage that are not covered under the new regulations. If you receive your vaccine from a doctor’s office or urgent care clinic, talk to them about a possible hidden fee. To ensure that you do not get a surprise bill, the best bet is to get your vaccine delivered to the health department’s vaccination site or local pharmacy after shots become more widely available.

It is to be determined. It is possible that the Kovid-19 vaccination will become an annual phenomenon like the flu pill. Or it may be that the benefits of the vaccine stay for more than a year. We will have to wait to see how durable the protection from vaccines is. To determine this, researchers are going to monitor vaccinated people to look for “cases of success” – people who get sick from Kovid-19 despite being vaccinated. This is a sign of weakening safety and will give researchers clues about how long the vaccine lasts. They will monitor the levels of antibodies and T cells in the blood of vaccinated people to determine if and when a booster shot may be required. It is predictable that people may need boosters every few months, once a year or only a few years. It is just a matter of waiting for the data.

Among other efforts, Mr. Ziers said the government has now made sure that special syringes have been sent out along with Pfizer vials so that doctors can extract a sixth dose from them. Pfizer chief executive Albert Borla told investors on Tuesday that the company was now two months ahead of schedule and expected to deliver a total of 200 million doses for Americans by the end of July through the end of May. The acceleration is at least partly because the government has decided to count Pfizer’s vial as six doses instead of five.

The introduction of pharmacies will usher in a new phase in the nation’s vaccination campaign. Until now the campaign was focused on hospitals, other health care facilities and large venues such as stadiums. Officials expect smaller settings such as pharmacies to play a role faster.

Some states are already dosing to a limited number of pharmacies; Officials said the federal program would not cut dose supplies.

The program will be slow to begin at first – many pharmacies will not have all the vaccines or have very limited supplies, Mr. Zeers said – and it will still not expand to the limited number of high-risk groups that states have deemed receiving vaccines. To be eligible for. Eligible patients should check pharmacy websites for availability, Mr. Zients said.

Mr Zients said the federal government would allocate vaccines under the pharmacy program based on the population of each state and jurisdiction, as it did for vaccines distributed through other channels.

The Center for Disease Control and Prevention is also working closely with the states to select pharmacies in areas that are “hard to reach” and close to those at high risk of severe cases of Kovid-19, Mr. Zeers he said. He said the agency would monitor the program to ensure that pharmacies were delivering the dose efficiently and inexpensively.

Dozens of pharmacies and grocery stores, including both national and regional chains, are participating in the program, but not all will be involved in its initial phase. These include CVS, Walgren, Walmart, Reit Aid, Kroger, Publics, Meijer, Costco, Jewel-Osco and Safeway.

The expansion of the vaccine rollout to more retail pharmacies will present new logistical challenges, as well as many who have ended the rollout so far. The vaccine needs to be found in its stores or other locations to deliver the vaccine. They will need to document the shots carefully, as well as remind people to return for their second dose. Pharmacists and support staff will need to keep people socially disturbed and see them later for side effects – while also handling all the usual demands of a busy drug.

A Minnesota pharmacist, Adam Nachand, who has spent much of his 20-year career working in retail, said, “It’s not just a matter of pulling a syringe. Pharmacies and long-term care for Walgren currently Doing vaccines in facilities. “You still need to be able to manage that with enough time to deliver care, screening, answering their questions, monitoring them, etc. – and you have a run. Is still a pharmacy. “

Sharon Lafranier And Noah Weiland Reported from Washington, and Rebecca Robbins From Bellingham, wash off. Katie Thomas Contributed to reporting from Chicago.

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