Delayed Skin Reactions Appear After Vaccine Shots

Some people are having a delayed reaction to the first dose of a Kovid vaccine, their hands are red, sore throat, itchy and swollen a week after the pill.

Although unpleasant reactions appear to be harmless. But angry skin conditions can be mistaken for infection. A letter was published on Wednesday In The New England Journal of Medicine. Doctors said they wanted to share information about the cases to prevent unnecessary use of antibiotics and to help ease patients’ concerns and reassure them that they could safely take their second vaccine shot.

A writer at Massachusetts General Hospital and an allergy specialist, Drs. Kimberly “We changed our patient once we saw it,” Brenthal said in an interview. “We said that redness, itching, and swelling were normal when you received the vaccine. We changed the word to say that you can start seven to 10 days after getting the vaccine.”

The letter described the experiences of 12 people who had “delayed large local reactions” that began four to 11 days after the first shot of the modern vaccine, in the middle of eight days. The report is not a controlled study, but rather a series of cases that came to the attention of doctors as those receiving the vaccine were concerned and wanted to know if they should get a second shot.

Most were vaccinated at Massachusetts General Hospital, where both modern and Pfizer-Bioentech vaccines were administered. But the delayed reactions occurred only in people receiving modern shots, Drs. Blumental said, “I don’t understand why.”

Moderna reported delayed skin reactions Large diagnostic test 0.8 percent in recipients after the first dose and 0.2 percent after the second dose.

Dr. According to the letter from Blumenthal and 10 other physicians, all 12 people reported specific symptoms like a sore throat that often occur immediately after vaccination, and those initial symptoms had disappeared.

Then, a delayed response hit. In five people, large, bulging skin lesions have emerged that are measured 10 or more centimeters in diameter near the injection site. There were rashes in two other places, one near the elbow and one on the palm of the hand. Some also had systemic symptoms at the same time, such as fatigue and muscle pain.

Most treated skin symptoms with ice and antihistamines. But some required steroid, cream or pill form, and one was prescribed an antibiotic by a doctor who mistook the problem for infection.

Symptoms lasted between six days, ranging from two days to 11 days. All patients went to take the second shot. Nimmi did not have another delayed reaction, but all three developed the same symptom and three still reacted after the first shot.

Dr. Blumental said there were many unanswered questions about the responses. Ten of the 12 patients were women, but it is unclear whether women are at greater risk of the problem or whether there has been an imbalance because more of the vaccinated health workers were women.

Some were allergic to drugs, wasp stings or food, but others did not.

A skin biopsy on a patient indicated that the condition was a drug reaction. But exactly what the patient’s immune system was responding to is not known.

“I hope companies will find out,” Dr. Blumental said.

He said about 30 cases are now known, mostly among women and all recipients of the modern vaccine, he said, and the hospital has built one Registry to track them.

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