“We don’t necessarily know that in fact very few populations have low symptomatology,” she said.
Similarly the reasons behind the unclear study are that in the first wave of MIS-C from March 1 to July 1, 2020, young people suffered from some of the most serious cardiovascular complications. Dr. DeBacy said that did not match his hospital experience, where “the children were ill in the second wave.”
The study documented two waves of MIS-C cases that increased in coronovirus cases after about a month or longer. The authors wrote, “The most recent third peak of the Kovid-19 epidemic leads to another MIS-C peak, which probably includes urban and rural communities.”
The study found that the majority of states where MIS-C cases had the highest rate per population were in the Northeast, with the first increase in cases, and the South. In contrast, most states with high per-population rates of children with covid-19 but low rates of MIS-C were in the Midwest and West. Although the concentration of cases spread from large cities to small towns over time, it was not clear as to the overall epidemic trends.
Dr. Blumenthal said the geographic pattern could indicate that the “understanding of the complications of the disease” was not captured for its prevalence in different regions or that many states with low rates of MIS-C have low ethnically diverse populations. “It could also be something about Kovid himself, although we don’t know that,” she said. “Right now, we don’t know anything about how children are affected.”
The study represented only the strictest criteria for MIS-C, except for approximately 350 reported cases that met the CDC definition of the syndrome, but included a negative antibody test or predominantly respiratory symptoms. Dr. Debiasi said that there are also a number of potential MIS-C cases that are not reported to the CDC because they do not meet all official criteria.
“These potential MIS-C kids, it’s a big part of the kids in real life,” she said. Furthermore, while serious cases have so far been focused on, “there is another whole group of children who may actually have mild MIS-C.”
If a community has recently experienced coronovirus growth, “just because the child says, ‘I’ve never had a Kovid or my parents never had,'” doesn’t mean your There is no MIS-C of the child in front, dr. Debiasi said. “If you have a Kovid in your city, then get ready.”